تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Do eosinophil counts correlate differently with asthma severity by symptoms versus peak flow rate?
Do eosinophil counts correlate differently with asthma severity by symptoms versus peak flow rate?
 
لغة الوثيقة : الانجليزية 
المستخلص : BACKGROUND: Discrepancy in asthmatic assessment by symptoms and peak flow rate (PFR) is a frequent dilemma. Currently, total peripheral eosinophil count (TPEC) is under study for asthma evaluation. OBJECTIVES: To explore the correlation between TPEC and asthma severity assessed by symptoms alone versus symptoms and PFR. METHOD: Adults asthmatics were selected from the Asthma Clinic. Severity assessment was based on two methods: symptoms alone or symptoms and PFR. Expiratory PFR was recorded by a Wright peak flow meter. Severity levels included mild intermittent, mild persistent, moderate persistent, and severe persistent. Total peripheral eosinophil count was performed on a Celldyn-3500 counter. Data was analyzed for statistical significance. RESULTS: Sixty asthmatics aged 15 to 70 years (mean = 34 years), of which 68.3% were female, were studied. Severity levels differed between the two assessment methods in 45% of the cases and showed a predominance of the moderate persistent type. Total peripheral eosinophil count ranged between 22 and 2470 cells/mm3 (mean = 520 +/- SD = 393) and eosinophilia was found in 50% of the cases. Total peripheral eosinophil count showed a high positive correlation with increased asthma severity level assessed by history alone (r = 0.460, P < .001); more than by history and PFR (r = 0.328, P < .05). CONCLUSION: The discrepancy between symptoms and PFR is confirmed by these results. A reliable objective parameter in asthma assessment is a continuous challenge. This study advocates the possible supplementation of TPEC as another objective parameter that might help in selecting the appropriate severity level in asthmatics 
ردمد : 1081-1206 
اسم الدورية : Annals of Allergy, Asthma and Immunology 
المجلد : 83 
العدد : 1 
سنة النشر : 1420 هـ
1999 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Friday, October 16, 2009 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
عماد كوشكKoshak, Emad باحث رئيسيدكتوراه 
عمر العموديAlamoudi, Omer باحث مشاركدكتوراه 

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